This romantic drama focuses on the lives and loves of a seemingly disparate group of people living in Los Angeles. Among the characters are a mature couple about to renew their vows (Sean Connery and Gena Rowlands); a woman (Gillian Anderson) who accepts a date offer from a madcap stranger (Jon Stewart); a man dying of AIDS (Jay Mohr) and his mother (Ellen Burstyn) who has struggles to accept him; two clubbers who meet in a nightclub (Ryan Phillippe and Angelina Jolie); a couple having an affair (Anthony Edwards and Madeleine Stowe) and a man (Dennis Quaid) who tells his tragic life story to a woman he meets in a bar (Patricia Clarkson), but seems to have a strange connection to another mysterious woman. As the film continues and the stories evolve, the connections between the characters become evident.